The gallery was founded in 1975 by Elena and Felix Buchmann in St. Gallen, Switzerland. Between 1983 and 1998 the gallery was located in Basel next to the Museum of Contemporary Art; today it has two branches in Agra/Lugano and in Lugano.

André Buchmann founded the Buchmann Galerie in Germany in 1995, setting up in premises in Cologne. Since 2005 the gallery has been located in Berlin, where it has two centrally located exhibition rooms in Charlottenstrasse between Checkpoint Charlie and Gendarmenmarkt. André Buchmann has been a member of the board of the Cragg Foundation Wuppertal since 2008.

The Buchmann Galerie represents international emerging and established artists, most of whom work with sculpture, painting, video and photography. The artists represented by the Berlin gallery include:

Anna & Bernhard Blume, Daniel Buren, Lawrence Carroll, Tony Cragg, The Estate of Martin Disler, Alberto Garutti, Raffi Kalenderian, Wolfgang Laib, Tatsuo Miyajima, Wilhelm Mundt, Bettina Pousttchi, Fiona Rae, Joel Sternfeld, William Tucker, Clare Woods.

The gallery has been working with many of these artists from a very early point in their career. The Buchmann Galerie has worked with Tony Cragg since 1983, with Wolfgang Laib since 1987, with Fiona Rae since 2000, with Tatsuo Miyajima since 1994, with Bettina Pousttchi since 2005, with Lawrence Carroll since 1994, with Daniel Buren since 1989. The gallery has also represented the estate of Martin Disler since 2013.

The artists are included in exhibitions at institutions all around the world and have been shown at major art shows, including the Venice Biennale, DocumentaKassel, Carnegie International Pittsburg and Prospect in New Orleans. They have received important art prizes, including the most prestigious award of all, the Praemium Imperiale. This prize was awarded to three artists represented by the gallery: Daniel Buren (2007), Tony Cragg (2007), Wolfgang Laib (2015).